HIERARCHICAL MACHINE LEARNING SYSTEM FOR FUNCTIONAL DIAGNOSIS OF EYE PATHOLOGIES BASED ON THE INFORMATIONEXTREMAL APPROACH

Authors

  • I. V. Shelehov Sumy National Agrarian University,Sumy,Ukraine; Sumy State University,Ukraine, Ukraine
  • D. V. Prylepa Sumy State University, Sumy, Ukraine, Ukraine
  • Y. O. Khibovska Sumy State University, Sumy, Ukraine, Ukraine
  • O. A. Tymchenko Sumy State University,Sumy,Ukraine, Ukraine

DOI:

https://doi.org/10.15588/1607-3274-2025-3-11

Keywords:

computer diagnosis of eye pathologies,, artificial intelligence, machine learning, image processing, pattern recognition, information-extremal technology, hierarchical classifier structure

Abstract

Context. The task of information-extremal machine learning for the diagnosis of eye pathologies based on the characteristic signs of diseases is considered. The object of the study is the process of hierarchical machine learning in the system for diagnosing ophthalmological diseases. The aging population and the increasing prevalence of eye diseases, such as glaucoma,  optic nerve atrophy, retinal detachment, and diabetic retinopathy, necessitate effective methods for early diagnosis to prevent vision loss. Traditional diagnostic methods largely rely on the experience of the physician, which can lead to errors. The use of artificial intelligence (AI) and machine learning (ML) can significantly improve the accuracy and speed of diagnosis, making this topic highly relevant.
Objective. To enhance the functional efficiency of a computerized system for diagnosing eye pathologies based on image data.
Method. A method of information-extremal hierarchical machine learning for a system of eye pathology diagnosis based on the characteristic signs of diseases is proposed. The method is based on a functional approach to modeling cognitive processes of natural intelligence, ensuring the adaptability of the diagnostic system under any initial conditions for the formation of pathology images and allowing flexible retraining of the system when the recognition class alphabet expands. The foundation of the method is the principle of maximizing the criterion of functional efficiency based on a modified Kullback information measure, which is a functional of the diagnostic rule precision characteristics. The learning process is considered as an iterative procedure for optimizing the parameters of the diagnostic system’s operation according to this information criterion. Based on the proposed categorical functional model, an information-extremal machine learning algorithm with a hierarchical data structure in the form of a binary recursive tree is developed. This data structure enables the division of a large number of recognition classes into pairs of nearest neighbors, for which the machine learning parameters are optimized using a linear algorithm of the necessary depth.
Results. An intelligent technology for diagnosing eye pathologies has been developed, which includes a comprehensive set of information, algorithmic, and software components. A comparative analysis of the effectiveness of different methods for organizing decision rules during system training has been conducted. It was found that the use of recursive hierarchical classifier structures allows achieving higher diagnostic accuracy compared to binary classifiers.
Conclusions. The developed intelligent computer-based diagnostic system for eye pathologies demonstrates high efficiency and accuracy. The implementation of such a system in medical practice could significantly improve the quality of eye disease diagnostics, reduce the workload on physicians, and minimize the risk of misdiagnosis. Further research could focus on refining algorithms and expanding their application to other types of medical images

Author Biographies

I. V. Shelehov, Sumy National Agrarian University,Sumy,Ukraine; Sumy State University,Ukraine

PhD, Associate Professor of the Department of Cybernetics and Informatics Department;                             PhD, Associate Professor at the Computer Science Department

D. V. Prylepa, Sumy State University, Sumy, Ukraine

PhD, Assistant at the Computer Sciences Department

Y. O. Khibovska, Sumy State University, Sumy, Ukraine

Postgraduate student at the Department of Computer Science

O. A. Tymchenko, Sumy State University,Sumy,Ukraine

Postgraduate student at the Department of Computer Science

References

Lírio L. R. de, Malheiros É. F. R., Stabile G. et al. Retinoblastoma e a radiologia intervencionista: papel no tratamento da população infantil, Brazilian Journal of Implantology and Health Sciences, 2024, Vol. 8, № 6, pp. 3380–3399. DOI: 10.36557/2674 8169.2024v6n8p3380-3399.

Stitt A. W., Lois N., Medina R. J. et al. Advances in Our Understanding of Diabetic Retinopathy, Clin Sci (Lond), 2013, Vol. 125, №1, pp. 1–17. DOI: 10.1042/CS20120588.

Cho N. H., Shaw J. E., Karuranga S. et al. IDF Diabetes Atlas: Global Estimates of Diabetes Prevalence for 2017 and Projections for 2045, Diabetes Research and Clinical Practice, 2018, Vol. 138, pp. 271–281. DOI: 10.1016/j.diabres.2018.02.023.

Oshika T. Artificial Intelligence Applications in Ophthalmology, JMAJ, 2025, Vol. 8, № 1, pp. 66–75. DOI: 10.31662/jmaj.2024-0139.

Li Z., Wang L., Wu X. et al. Artificial Intelligence in Ophthalmology: The Path to the Real-World Clinic, Cell Reports Medicine, 2023, Vol. 4, № 7, Article number: 101095. DOI: 10.1016/j.xcrm.2023.101095.

Srivastava O., Tennant M., Grewal P. et al. Artificial Intelligence and Machine Learning in Ophthalmology: A Review, Indian Journal of Ophthalmology, 2023, Vol. 71, №1, pp. 11–17. DOI: 10.4103/ijo.IJO_1569_22.

Shelehov I. V., Prylepa D. V., Khibovska Y. O. et al. Machine learning decision support systems for adaptation of educational content to the labor market requirements, Radio Electronics, Computer Science, Control, 2023, Vol. 1, pp. 62–72. DOI: 10.15588/1607-3274-2023-1-6.

Prylepa D.V. Informatsiyno-ekstremal’na intelektual’na tekhnolohiya diahnostuvannya emotsiyno-psykhichnoho stanu lyudyny. Dys. c.t.n. [Information-extreme intellectual technology for diagnosing the emotional and mental state of a person. Candidate of Technical Sciences diss.]. Kharkiv, 2024. 188 p.

Shelehov I. V., Barchenko N. L., Prylepa D. V. et al. Information-extreme machine training system of functional diagnosis system with hierarchical data structure, Radio Electronics, Computer Science, Control, 2022, Vol. 2, pp. 189– 200. DOI: 10.15588/1607-3274-2022-18.

Chandra A., Romano M. R., Chao D. L. Implementing the New Normal in Ophthalmology Care Beyond COVID-19, European Journal of Ophthalmology, 2020, Vol. 31, № 2. DOI: 10.1177/1120672120975331.

Bejnordi B. E., Zuidhof G., Balkenhol M. et al. Context-Aware Stacked Convolutional Neural Networks for Classification of Breast Carcinomas in Whole-Slide Histopathology Images, Journal of Medical Imaging, 2017, Vol. 4, № 4, pp. 1. DOI: 10.1117/1.jmi.4.4.044504.

Gu H., Gu Y., Wei A. et al. Deep Learning for Identifying Corneal Diseases from Ocular Surface Slit-Lamp Photographs, Scientific Reports, 2020, Vol. 10, Article number: 17851. DOI: 10.1038/s41598-020-75027-3.

Kermany D. S., Goldbaum M., Cai W. et al. Identifying Medical Diagnoses and Treatable Diseases by Image-Based Deep Learning, Cell, 2018, Vol. 172, №5, pp. 1122–1131.e9. DOI: 10.1016/j.cell.2018.02.010.

Gulshan V., Peng L., Coram M. et al. Development and Validation of a Deep Learning Algorithm for Detection of Diabetic Retinopathy in Retinal Fundus Photographs, JAMA, 2016, Vol. 316, №22, pp. 2402–2410. DOI: 10.1001/jama.2016.17216.

Woreta F. A., Gordon L. K., Pérez-González C. E. Enhancing Diversity in the Ophthalmology Workforce, Ophthalmology, 2022, Vol. 129, №10, pp. 127–136. DOI: 10.1016/j.ophtha.2022.06.033.

Lu W., Tong Y., Yu Y. et al. Applications of Artificial Intelligence in Ophthalmology: General Overview, Journal of Ophthalmology, 2018, Article number: 30581604, pp. 1–15. DOI: 10.1155/2018/5278196.

Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes-2019, Diabetes Care, 2019, Vol. 42(Supplement 1), pp. 13–28. DOI: 10.2337/dc19-s002.

Kermany D. S., Goldbaum M., Cai W. et al. Identifying Medical Diagnoses and Treatable Diseases by Image-Based Deep Learning, Cell, 2018, Vol. 172, №5, pp. 1122–1131.e9. DOI: 10.1016/j.cell.2018.02.010.

Putivets’, A.V. Intelektual’na systema vyyavlennya urazhen’ sitkivky oka: robota na zdobuttya kvalifikatsiynoho stupenya bakalavra; spets.: 122 – komp"yuterni nauky (informatyka) [Elektron. resurs] / A.V. Putivets’; nauk. kerivnyk I.V. Shelekhov. – Sumy: SumDU, 2020. – 72 s. – Rezhym dostupu: http://essuir.sumdu.edu.ua:8080/handle/123456789/79779.

Suprunenko M. K., Zborshchyk O. P., Sokolov O. Informationextreme machine learning of wrist prosthesis control system based on the sparse training matrix, Journal of Engineering Sciences, 2022, Vol. 9, iss. 2, pp. 28–35. DOI: 10.21272/jes.2022.9(2).e4.

Dovbysh A., Zimovets V. Hierarchical Algorithm of the Machine Learning for the System of Functional Diagnostics of the Electric Drive, Advanced Information Systems and Technologies, VI International Conference, Sumy, 16–18 May 2018: proceedings, Sumy, Sumy State University, 2018, pp. 85– 88.

Moskalenko V. V., Moskalenko A. S., Korobov A. G. Models and methods of intellectual information technology of autonomous navigation for compact drones, Radio Electronics, Computer Science, Control, 2018, № 3, pp. 68–77. DOI: 10.15588/1607-3274-2018-3-8.

Dovbysh A., Shelehov I., Romaniuk A., et al. Decision-making support system for diagnosis of oncopathologies by histological images, Journal of Pathology Informatics, 2023, Article number: 100193. DOI: 10.1016/j.jpi.2023.100193.

Shelehov I., Prylepa D., Khibovska Y. et al. InformationExtreme Machine Learning of an Ophthalmic Diagnostic System with a Hierarchical Class Structure, Artificial Intelligence, 2024, № 3, pp. 114–125. DOI: 10.15407/jai2024.03.114.

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Published

2025-09-22

How to Cite

Shelehov, I. V., Prylepa, . D. V. ., Khibovska, Y. O. ., & Tymchenko, O. A. (2025). HIERARCHICAL MACHINE LEARNING SYSTEM FOR FUNCTIONAL DIAGNOSIS OF EYE PATHOLOGIES BASED ON THE INFORMATIONEXTREMAL APPROACH. Radio Electronics, Computer Science, Control, (3), 112–125. https://doi.org/10.15588/1607-3274-2025-3-11

Issue

Section

Neuroinformatics and intelligent systems